PRECAUTIONS WITH METFORMIN (GLUCOPHAGE)

Q:  If I am taking Metformin (Glucophage) for diabetes, can I receive contrast material?

A:    Yes, but only if certain precautions are taken and if there are no other contraindications to iodinated contrast material, such as abnormal renal function or history of previous contrast reaction. Metformin (Glucophage) is an oral antihyperglycemic agent used to treat patients with non-insulin-dependent diabetes. There is an uncommon but serious adverse effect of lactic acidosis, possibly leading to death, in patients who do not discontinue their Metformin medication following injection of contrast material. Metformin (Glucophage) must be discontinued before or at the time of the contrast injection, and withheld for 48 hours after the injection. If you have any questions regarding this medication interruption or the management of your diabetes during this time period, please contact your personal physician.